LYPLA1

LYPLA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1FJ2
Identifiers
Aliases	LYPLA1, APT-1, APT1, LPL-I, LPL1, hAPT1, lysophospholipase I, lysophospholipase 1
External IDs	OMIM: 605599; MGI: 1344588; HomoloGene: 100781; GeneCards: LYPLA1; OMA:LYPLA1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	54,102,017 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	4,918,633 bp
RNA expression pattern
	Top expressed in
	human penis; ; oral cavity; ; gonad; ; vulva; ; right ventricle; ; skin of thigh; ; mucosa of sigmoid colon; ; epithelium of nasopharynx; ; superior surface of tongue; ; biceps brachii;
	Top expressed in
	right kidney; ; gallbladder; ; superior surface of tongue; ; intercostal muscle; ; jejunum; ; epithelium of small intestine; ; cardiac muscle tissue of left ventricle; ; gastrula; ; extensor digitorum longus muscle; ; plantaris muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	lysophospholipase activity; hydrolase activity; lipase activity; palmitoyl-(protein) hydrolase activity; carboxylic ester hydrolase activity; protein binding;
Cellular component	cytoplasm; cytosol; extracellular exosome; mitochondrion;
Biological process	protein depalmitoylation; regulation of nitric-oxide synthase activity; negative regulation of Golgi to plasma membrane protein transport; fatty acid metabolic process; lipid metabolism; metabolism;
	Sources:Amigo / QuickGO
Orthologs
	10434
	18777
	ENSG00000120992
	ENSMUSG00000025903
	O75608; Q6IAQ1
	P97823
NM_001279356; NM_001279357; NM_001279358; NM_001279359; NM_001279360;
	NM_006330
	NM_008866; NM_001355712
NP_001266285; NP_001266286; NP_001266287; NP_001266288; NP_001266289;
	NP_006321; NP_006321.1
	NP_032892; NP_001342641
	Wikidata
View/Edit Human	View/Edit Mouse

Acyl-protein thioesterase 1 is an enzyme that in humans is encoded by the LYPLA1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120992 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025903 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang A, Yang HC, Friedman P, Johnson CA, Dennis EA (Apr 1999). "A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization". Biochim Biophys Acta. 1437 (2): 157–69. doi:10.1016/s1388-1981(99)00012-8. PMID 10064899.
^ "Entrez Gene: LYPLA1 lysophospholipase I".

References

Further reading