Ladeana Hillier

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Ladeana Hillier is a biomedical engineer and computational biologist.[1] She was one of the earliest scientists involved in the Human Genome Project[2] and is noted for her work in various branches of DNA sequencing,[3][4][5][6][7] as well as for having co-developed Phred,[8] a widely used DNA trace analyzer.[9][10]

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  1. ^ Wenz, C (2005) Author Profile: Ladeana Hillier. Nurture 1, pp. 2.
  2. ^ Sulston, J and Ferry, G (2002) The Common Thread: A Story of Science, Politics, Ethics, and the Human Genome, Joseph Henry Press.
  3. ^ Hillier, LW et al. (2003) The DNA sequence of human chromosome 7. Nature 424(6945), 157–164.
  4. ^ Hillier, LW et al. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature 434(7034), 724–731.
  5. ^ Hillier, LW et al. (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432(7018), 695–716.
  6. ^ Hillier, LW et al. (2008) Whole-genome sequencing and variant discovery in C-elegans. Nature Methods 5(2), 183–188.
  7. ^ Hillier, LW et al. (1996) Generation and analysis of 280,000 human expressed sequence tags. Genome Research 6(9), 807–828.
  8. ^ Ewing, B., Hillier, L., Wendl, M.C., and Green, P. (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Research 8(3), 175–185. PMID 9521921 full article
  9. ^ Koboldt, D. C. and Miller, R. D. (2011) Identification of Polymorphic Markers for Genetic Mapping, chapter 2 in "Genomics: Essential Methods", John Wiley and Sons.
  10. ^ Highsmith, W. E. (2006) Electrophoretic Methods for Mutation Detection and DNA Sequencing, chapter 9 in "Molecular Diagnostics for the Clinical Laboratorian", Humana Press

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