Henry was born in Elmira, New York. He graduated from Cornell University in 1909, where he was a member of The Kappa Alpha Society and president of the Quill and Dagger society. He received a law degree from Columbia University in 1911. He was supervisor of Elmira's first ward from 1914 until 1920. He was elected to Congress in 1922 to fill the vacancy caused by the resignation of Alanson B. Houghton and served from April 11, 1922, until March 4, 1923. He died in Boston, Massachusetts.
- United States Congress. "Lewis Henry (id: H000510)". Biographical Directory of the United States Congress.
- Lewis Henry at Find a Grave