List of SJS-inducing substances

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This is a list of drugs and substances that are known to be, or are suspected to be implicated in causing Stevens–Johnson syndrome.

Name Certainty of implication Other names
Acetaminophen Certain [1] [2] Paracetamol, Tylenol
Allopurinol Certain [3]
Amoxicillin Certain [4]
Ampicillin Certain [4]
Azithromycin Certain[citation needed]
Barbiturates Certain[citation needed]
Carbamazepine Certain[citation needed]
Ciprofloxacin/levofloxacin/Gemifloxacin Certain[citation needed]
Diclofenac Certain [5]
Ethosuximide Certain[citation needed]
Ibuprofen Certain [6]
Isotretinoin Certain [7] Accutane
Lamotrigine Certain [8] Lamictal
Modafinil Certain [9] Provigil
Nevirapine Certain[citation needed]
Oseltamivir Certain[citation needed]
Penicillins Certain[citation needed]
Phenytoin Certain[citation needed]
Sitagliptin Certain[citation needed]
Sulfonamides Certain [4]
Tetracycline Certain [4]
  1. ^ "Acetaminophen-induced Steven Johnson syndrome-toxic epidermal necrolysis overlap". J Pak Med Assoc. 
  2. ^ "Stevens-Jonhson syndrome after acetaminophen ingestion, confirmed by challenge test in an eleven-year-old patient". the Journal: Allergologia et Immunopathologia. 
  3. ^ Harr T, French LE (2012). "Adverse Cutaneous Drug Eruptions". Chem Immunol Allergy (Karger, Basel) 97 (1): 149–166. doi:10.1159/000335627. PMID 22613860.  |chapter= ignored (help)
  4. ^ a b c d "Stevens Johnson Syndrome". WebMD. 
  5. ^ Roujeau, J.-C., Kelly, J. P., Naldi, L., Rzany, B., Stern, R. S., Anderson, T., Auquier, A., Bastuji-Garin, S., Correia, O., Locati, F., Mockenhaupt, M., Paoletti, C., Shapiro, S., Shear, N., Schopf, E., Kaufman, D. W. (1995). "Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.". New Eng J Med 333 (1): 1600–1607. doi:10.1056/NEJM199512143332404. PMID 7477195. 
  6. ^ Raksha MP, Marfatia YS (2008). "Clinical study of cutaneous drug eruptions in 200 patients". Indian J Dermatol Venereol Leprol 74 (1): 80. doi:10.4103/0378-6323.38431. PMID 18193504. 
  7. ^ Medsafe Data Sheet March 8, 2005. Accessed April 26, 2007.
  8. ^ "LAMICTAL PRESCRIBING INFORMATION" (PDF). GlaxoSmithKline. 
  9. ^ "PROVIGIL PRESCRIBING INFORMATION" (PDF). Cephalon, Inc.