List of Ultratop 50 number-one singles of 2005
These hits topped the Ultratop 50 charts in 2005 (see 2005 in music).[1]
| Issue Date | Artist | Song |
| January 1 | Joeri Fransen | Ya 'bout to find out |
| January 8 | Joeri Fransen | Ya 'bout to find out |
| January 15 | Joeri Fransen | Ya 'bout to find out |
| January 22 | Artiesten Voor Tsunami 12-12 | Geef een teken (Give Me a Sign) |
| January 29 | Artiesten Voor Tsunami 12-12 | Geef een teken |
| February 5 | Artiesten Voor Tsunami 12-12 | Geef een teken |
| February 12 | Artiesten Voor Tsunami 12-12 | Geef een teken |
| February 19 | Artiesten Voor Tsunami 12-12 | Geef een teken |
| February 26 | Schnappi | Das kleine Krokodil |
| March 5 | Schnappi | Das kleine Krokodil |
| March 12 | Schnappi | Das kleine Krokodil |
| March 19 | Schnappi | Das kleine Krokodil |
| March 26 | Schnappi | Das kleine Krokodil |
| April 2 | Schnappi | Das kleine Krokodil |
| April 9 | Schnappi | Das kleine Krokodil |
| April 16 | Schnappi | Das kleine Krokodil |
| April 23 | 50 Cent & Olivia | Candy shop |
| April 30 | Green Day | Boulevard of Broken Dreams |
| May 7 | Star Academy | Fame |
| May 14 | Star Academy | Fame |
| May 21 | Star Academy | Fame |
| May 28 | Star Academy | Fame |
| June 4 | Crazy Frog | Axel F |
| June 11 | Crazy Frog | Axel F |
| June 18 | Crazy Frog | Axel F |
| June 25 | Crazy Frog | Axel F |
| July 2 | Crazy Frog | Axel F |
| July 9 | Crazy Frog | Axel F |
| July 16 | Crazy Frog | Axel F |
| July 23 | Crazy Frog | Axel F |
| July 30 | Crazy Frog | Axel F |
| August 6 | Crazy Frog | Axel F |
| August 13 | Crazy Frog | Axel F |
| August 20 | Crazy Frog | Axel F |
| August 27 | James Blunt | You're beautiful |
| September 3 | James Blunt | You're beautiful |
| September 10 | James Blunt | You're beautiful |
| September 17 | James Blunt | You're beautiful |
| September 24 | James Blunt | You're beautiful |
| October 1 | The Pussycat Dolls & Busta Rhymes | Don't cha |
| October 8 | The Pussycat Dolls & Busta Rhymes | Don't cha |
| October 15 | Bob Sinclar | Love Generation |
| October 22 | Bob Sinclar | Love generation |
| October 29 | Bob Sinclar | Love generation |
| November 5 | Bob Sinclar | Love generation |
| November 12 | Bob Sinclar | Love generation |
| November 19 | Bob Sinclar | Love generation |
| November 26 | Madonna | Hung up |
| December 3 | Madonna | Hung up |
| December 10 | Madonna | Hung up |
| December 17 | Bob Sinclar | Love generation |
| December 24 | Bob Sinclar | Love generation |
| December 31 | Kippensoep Allstars | Kippensoep voor iedereen |