List of adverse effects of lurasidone
This is a list of adverse effects of the antipsychotic drug lurasidone, sorted by frequency of occurrence.[1][2][3]
Very common
Very common (>10% incidence) adverse effects include:
- Somnolence (dose-dependent; produces an intermediate degree of sedation compared to other atypical antipsychotics[4])
- Akathisia (dose-dependent)
- Fasting glucose increased
- Nausea
- Parkinsonism
Common
Common (1–10% incidence) adverse effects include:
- Weight gain
- Vomiting
- Dyspepsia
- Agitation
- Anxiety
- Dystonia
- Dizziness
- Fatigue
- Back pain
- Restlessness
- Hypersalivation
Uncommon
Uncommon (0.1–1% incidence) adverse effects include:
- Orthostatic hypotension
- Syncope
- Stroke
- Seizure
- Suicidal ideation
- Elevated serum creatinine
Rare
Rare (0.01–0.1% incidence) adverse effects include:
Unknown frequency
Unknown frequency adverse effects include:
- Transient ischaemic attack
- Hyperprolactinaemia (seems to be a rather prominent adverse effect according to a meta-analysis[4])
- Hypothermia
References
- ^ Truven Health Analytics, Inc. DrugPoint System (Internet) [cited 2013 Oct 1]. Greenwood Village, CO: Thomsen Healthcare; 2013.
- ^ lurasidone (Rx) - Latuda [Internet]. Medscape Reference. [cited 2013 Oct 1]. Available from: http://reference.medscape.com/drug/latuda-lurasidone-999605#4
- ^ LATUDA (lurasidone hydrochloride) tablet, film coated [Bushu Pharmaceutical, LTD.] [Internet]. DailyMed. 2010 [cited 2013 Oct 1]. Available from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=88a244d1-eddb-499c-bee2-e1f49056e78f
- ^ a b Leucht, S; Cipriani, A; Spineli, L; Mavridis, D; Orey, D; Richter, F; Samara, M; Barbui, C; Engel, RR; Geddes, JR; Kissling, W; Stapf, MP; Lässig, B; Salanti, G; Davis, JM (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis". Lancet. 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019.