MAGEA4

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MAGEA4
PDB 1i4f EBI.jpg
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases MAGEA4, CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MAGE family member A4
External IDs HomoloGene: 134073 GeneCards: MAGEA4
RNA expression pattern
PBB GE MAGEA4 214254 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001011548
NM_001011549
NM_001011550
NM_002362

n/a

RefSeq (protein)

NP_001011548
NP_001011549
NP_001011550
NP_002353

n/a

Location (UCSC) Chr X: 151.91 – 151.93 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene.[2][3]

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.[3]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ Rogner UC, Wilke K, Steck E, Korn B, Poustka A (Mar 1996). "The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28". Genomics. 29 (3): 725–31. doi:10.1006/geno.1995.9945. PMID 8575766. 
  3. ^ a b "Entrez Gene: MAGEA4 melanoma antigen family A, 4". 

Further reading[edit]