MGAT3

MGAT3
Identifiers
Aliases	MGAT3, GNT-III, GNT3, mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
External IDs	OMIM: 604621; MGI: 104532; HomoloGene: 31088; GeneCards: MGAT3; OMA:MGAT3 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	39,492,194 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	80,099,720 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; prefrontal cortex; ; Brodmann area 9; ; olfactory bulb; ; nucleus accumbens; ; cingulate gyrus; ; dorsal motor nucleus of vagus nerve; ; amygdala; ; anterior cingulate cortex;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; right kidney; ; primary visual cortex; ; cerebellar cortex; ; proximal tubule; ; supraoptic nucleus; ; lumbar subsegment of spinal cord; ; facial motor nucleus; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; glycosyltransferase activity; beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity;
Cellular component	integral component of membrane; Golgi membrane; Golgi apparatus; membrane;
Biological process	protein glycosylation; protein N-linked glycosylation; N-acetylglucosamine metabolic process; protein localization; regulation of cell migration; cellular response to oxidative stress; amyloid-beta metabolic process; cognition; positive regulation of protein localization to early endosome; negative regulation of lysosomal protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	4248
	17309
	ENSG00000128268
	ENSMUSG00000042428
	Q09327
	Q10470; Q5RKT9
	NM_001098270; NM_002409
	NM_010795
	NP_001091740; NP_002400
	NP_034925
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT3 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000128268 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042428 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ihara Y, Nishikawa A, Tohma T, Soejima H, Niikawa N, Taniguchi N (Oct 1993). "cDNA cloning, expression, and chromosomal localization of human N-acetylglucosaminyltransferase III (GnT-III)". J Biochem. 113 (6): 692–8. PMID 8370666.
^ "Entrez Gene: MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase".

References

Further reading