MPHOSPH8

MPHOSPH8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LWE, 3QO2, 3R93, 3SVM
Identifiers
Aliases	MPHOSPH8, HSMPP8, TWA3, mpp8, M-phase phosphoprotein 8
External IDs	OMIM: 611626; MGI: 1922589; HomoloGene: 11380; GeneCards: MPHOSPH8; OMA:MPHOSPH8 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	19,673,441 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	56,934,887 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; Achilles tendon; ; sural nerve; ; left ovary; ; right ovary; ; canal of the cervix; ; cerebellar hemisphere; ; gastric mucosa; ; body of uterus; ; right hemisphere of cerebellum;
	Top expressed in
	zygote; ; primary oocyte; ; secondary oocyte; ; facial motor nucleus; ; primitive streak; ; spermatocyte; ; substantia nigra; ; condyle; ; tail of embryo; ; fossa;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methylated histone binding; protein binding; ubiquitin protein ligase binding; ubiquitin-protein transferase activity; chromatin binding;
Cellular component	cytoplasm; plasma membrane; nucleolus; nucleus; chromosome; ubiquitin ligase complex; cytosol; heterochromatin;
Biological process	regulation of DNA methylation; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; protein ubiquitination; negative regulation of gene expression, epigenetic; positive regulation of DNA methylation-dependent heterochromatin assembly; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;
	Sources:Amigo / QuickGO
Orthologs
	54737
	75339
	ENSG00000196199
	ENSMUSG00000079184
	Q99549
	Q3TYA6
	NM_017520
	NM_023773; NM_001360072
	NP_059990
	NP_076262; NP_001347001
	Wikidata
View/Edit Human	View/Edit Mouse

M-phase phosphoprotein 8 is an enzyme that in humans is encoded by the MPHOSPH8 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196199 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000079184 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell. 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.
^ "Entrez Gene: HSMPP8 M-phase phosphoprotein, mpp8".

References

Further reading