MYBPC1

MYBPC1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1X44, 2DAV, 2YUV, 2YUW, 2YUX, 2YUZ, 2YXM
Identifiers
Aliases	MYBPC1, LCCS4, MYBPCC, MYBPCS, myosin binding protein C, slow type, ssMyBP-C, MYOTREM, myosin binding protein C1
External IDs	OMIM: 160794; MGI: 1336213; HomoloGene: 1846; GeneCards: MYBPC1; OMA:MYBPC1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	101,686,028 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	88,441,014 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; deltoid muscle; ; gastrocnemius muscle; ; glutes; ; vastus lateralis muscle; ; muscle of thigh; ; triceps brachii muscle; ; thoracic diaphragm;
	Top expressed in
	temporal muscle; ; ankle; ; soleus muscle; ; sternocleidomastoid muscle; ; digastric muscle; ; tibialis anterior muscle; ; extraocular muscle; ; thoracic diaphragm; ; vastus lateralis muscle; ; gastrocnemius muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; structural constituent of muscle; protein binding; titin binding; actin filament binding; muscle alpha-actinin binding; structural molecule activity conferring elasticity;
Cellular component	myosin filament; cytosol; myofibril; muscle myosin complex; Z discdkac; M band; striated muscle thin filament; sarcomere;
Biological process	cell adhesion; muscle contraction; muscle filament sliding; striated muscle contraction; actin filament organization; sarcomere organization; striated muscle myosin thick filament assembly; skeletal muscle thin filament assembly; skeletal muscle myosin thick filament assembly; cardiac myofibril assembly; cardiac muscle tissue morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	4604
	109272
	ENSG00000196091
	ENSMUSG00000020061
	Q00872
	n/a
NM_001254718; NM_001254719; NM_001254720; NM_001254721; NM_001254722;
	NM_001254723; NM_002465; NM_206819; NM_206820; NM_206821; NM_001404675; NM_001404676; NM_001404677; NM_001404678; NM_001404679; NM_001404680; NM_001404681
	NM_001252372; NM_175418
NP_001241647; NP_001241648; NP_001241649; NP_001241650; NP_001241651;
	NP_001241652; NP_002456; NP_996555; NP_996556; NP_996557
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-binding protein C, slow-type is a protein that in humans is encoded by the MYBPC1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196091 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020061 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Weber FE, Vaughan KT, Reinach FC, Fischman DA (Oct 1993). "Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment". Eur J Biochem. 216 (2): 661–9. doi:10.1111/j.1432-1033.1993.tb18186.x. PMID 8375400.
^ Flashman E, Watkins H, Redwood C (Dec 2006). "Localization of the binding site of the C-terminal domain of cardiac myosin-binding protein-C on the myosin rod". Biochem J. 401 (1): 97–102. doi:10.1042/BJ20060500. PMC 1698665. PMID 16918501.
^ "Entrez Gene: MYBPC1 myosin binding protein C, slow type".

References

Further reading