Makhado (also: Makhato or Magato, c.1839 – 3 September 1895) was a 19th century chief (or khosi) in the Singo (or Vhasenzi) dynasty of the Vendas. They ruled over the Dzanani "district" of the Zoutpansberg region of South Africa. He was the youngest son of khosi Ramabulana who died in 1864 when Makhado was about 25. Makhado's mother was Limani, noted for her political intrigue. Makhado’s first wife was Nwaphunga. According to Venda historian M. H. Nemudzivhadi, Nwaphunga conspired with a pro-Boer faction among the Venda, and poisoned him in 1895.
Limani was the daughter of the khosi of Tshitavhadulu. He intended her to become the new great wife of Ramabulana's younger brother Ramavhoya, then khosi, after her sister's passing. With the voortrekker Louis Tregardt's assistance, Ramabulana was able to overthrow Ramavhoya (who earlier had unseated him) and took the option to marry Limani.
- Thohoyandou the Great
- Munzhedzi Mpofu (khosi at Tshirululuni till 1829)
- Rasithu (also known as: Rasethau, Ramabulana, Ramapoelana, Munzhedzi and Ravele), ruled c.1830 and 1836–1864), Ramavhoya (ruled c.1830–1836) and Madzhie were sons of Mpofu
- Davhana and Makhado were sons of Ramabulana
- Maemu Malise, Alilali Tshilamulela (Mphephu I, or M'pefu), Sinthumule and Kutama were sons of Makhado
- Mbulaheni George (Mphephu II)
- Ramaano Patrick (Mphephu III, 1924–1988), president of Venda bantustan (1979–1988)
- Tshimangadzo (Dimbanyika Thohoyando II) and Toni (Mphephu Ramabulana)
- Braun, Lindsay F. (2014). Colonial Survey and Native Landscapes in Rural South Africa, 1850 - 1913: The Politics of Divided Space in the Cape and Transvaal (revised ed.). BRILL. pp. 252–255. ISBN 9789004282292.
- "Mphephu-Boer War, 1898". luonde.co.za. Luonde Vhavenda History. Retrieved 18 September 2016.
- Thohoyandou means "head of the elephant"
- Rasetau means "whose father is a lion"