Melarsomine

Melarsomine
Clinical data
Trade names	Immiticide
AHFS/Drugs.com	International Drug Names
ATC code	none;
Identifiers
	IUPAC name Bis(2-aminoethyl) {4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl}arsonodithioite;
CAS Number	128470-15-5;
PubChem CID	65962;
ChemSpider	59365;
UNII	374GJ0S41A;
KEGG	D08168 ;
CompTox Dashboard (EPA)	DTXSID40155907 ;
Chemical and physical data
Formula	C13H21AsN8S2
Molar mass	428.41 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=CC(=CC=C1NC2=NC(=NC(=N2)N)N)[As](SCCN)SCCN;
	InChI InChI=1S/C13H21AsN8S2/c15-5-7-23-14(24-8-6-16)9-1-3-10(4-2-9)19-13-21-11(17)20-12(18)22-13/h1-4H,5-8,15-16H2,(H5,17,18,19,20,21,22); Key:MGEOLZFMLHYCFZ-UHFFFAOYSA-N;
	(verify)

Melarsomine (melaminylthioarsenate) is a trypanocidal agent. It is marketed by Merial under the trade name Immiticide. As of 2015^[update], it is the only FDA-approved treatment for adult heartworm (Dirofilaria immitis) infection in dogs. It is not approved for treatment in cats, or dogs in late-stage infection.^[1]

References

^ Lawrence P. Tilley (2008). Manual of Canine and Feline Cardiology. Elsevier Health Sciences. pp. 194–197. ISBN 1-4160-2398-4.

External links

American Heartworm Society

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[Tilley2008-1] Lawrence P. Tilley (2008). Manual of Canine and Feline Cardiology. Elsevier Health Sciences. pp. 194–197. ISBN 1-4160-2398-4.

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