Myocardin

MYOCD
Identifiers
Aliases	MYOCD, MYCD, myocardin, MGBL
External IDs	OMIM: 606127 MGI: 2137495 HomoloGene: 17043 GeneCards: MYOCD
Gene location (Human) Chr. Chromosome 17 (human) Band 17p12 Start 12,665,890 bp End 12,768,949 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B3 Start 65,067,387 bp End 65,160,815 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein right ventricle nipple urethra right coronary artery superficial temporal artery ascending aorta smooth muscle tissue urinary bladder popliteal artery Top expressed in ascending aorta aortic valve belly cord myocardium of ventricle interventricular septum atrium vas deferens cumulus cell cardiac muscles atrioventricular valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription coactivator activity R-SMAD binding DNA-binding transcription activator activity, RNA polymerase II-specific transcription factor binding histone deacetylase binding core promoter sequence-specific DNA binding protein binding histone acetyltransferase binding cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding Cellular component nucleus Biological process cellular component maintenance positive regulation of transforming growth factor beta receptor signaling pathway response to hypoxia regulation of transcription, DNA-templated negative regulation of cyclin-dependent protein serine/threonine kinase activity urinary bladder development regulation of transcription by RNA polymerase II vascular associated smooth muscle cell differentiation cardiac ventricle development regulation of cell growth by extracellular stimulus positive regulation of DNA-binding transcription factor activity negative regulation of transcription by RNA polymerase II smooth muscle cell differentiation transcription, DNA-templated regulation of phenotypic switching vasculogenesis positive regulation of transcription, DNA-templated uterus development negative regulation of skeletal muscle cell differentiation negative regulation of cardiac muscle cell apoptotic process heart development muscle cell differentiation negative regulation of amyloid-beta clearance positive regulation of smooth muscle cell differentiation regulation of myoblast differentiation regulation of histone acetylation positive regulation of cell population proliferation negative regulation of myotube differentiation positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation positive regulation of cardiac vascular smooth muscle cell differentiation positive regulation of cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation positive regulation of DNA binding lung alveolus development digestive tract development positive regulation of smooth muscle contraction cardiocyte differentiation ductus arteriosus closure positive regulation of transcription by RNA polymerase II negative regulation of cell population proliferation regulation of smooth muscle cell differentiation transcription by RNA polymerase II cardiac muscle cell differentiation positive regulation of gene expression negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation of platelet-derived growth factor receptor-beta signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 93649 214384 Ensembl ENSG00000141052 ENSMUSG00000020542 UniProt Q8IZQ8 Q8VIM5 RefSeq (mRNA) NM_001146312 NM_001146313 NM_153604 NM_001378306 NM_145136 NM_146386 RefSeq (protein) NP_001139784 NP_705832 NP_001365235 NP_660118 NP_666498 Location (UCSC) Chr 17: 12.67 – 12.77 Mb Chr 11: 65.07 – 65.16 Mb PubMed search
Wikidata
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Myocardin is a protein that in humans is encoded by the MYOCD gene.