NLGN4X

NLGN4X
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2WQZ, 2XB6, 3BE8
Identifiers
Aliases	NLGN4X, ASPGX2, AUTSX2, HLNX, HNL4X, NLGN4, neuroligin 4, X-linked, neuroligin 4 X-linked
External IDs	OMIM: 300427; HomoloGene: 136297; GeneCards: NLGN4X; OMA:NLGN4X - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	6,228,867 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; spinal ganglia; ; cerebellar vermis; ; entorhinal cortex; ; ventricular zone; ; secondary oocyte; ; decidua; ; Brodmann area 46; ; buccal mucosa cell;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; scaffold protein binding; carboxylic ester hydrolase activity; neurexin family protein binding; protein binding; chloride ion binding; cell adhesion molecule binding; signaling receptor activity;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; postsynaptic density; synapse; integral component of plasma membrane; excitatory synapse; cell surface; cell junction; dendrite; plasma membrane; intracellular anatomical structure; spanning component of membrane; presynapse; symmetric, GABA-ergic, inhibitory synapse; asymmetric, glutamatergic, excitatory synapse;
Biological process	cell-cell junction organization; organ growth; neuron cell-cell adhesion; brainstem development; synapse organization; learning; cerebellum development; negative regulation of excitatory postsynaptic potential; presynaptic membrane assembly; vocalization behavior; adult behavior; cell adhesion; neuron differentiation; social behavior; synaptic vesicle endocytosis; postsynaptic membrane assembly; modulation of chemical synaptic transmission; presynapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	57502
	n/a
	ENSG00000146938
	n/a
	Q8N0W4
	n/a
	NM_001282145; NM_001282146; NM_020742; NM_181332
	n/a
	NP_001269074; NP_001269075; NP_065793; NP_851849
	n/a
	Wikidata
View/Edit Human

Neuroligin-4, X-linked is a protein that in humans is encoded by the NLGN4X gene.^[3]^[4]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146938 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (Jan 2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
^ "Entrez Gene: NLGN4X neuroligin 4, X-linked".

References

Further reading