NRS may refer to:
- NetherRealm Studios, an American video game developer known for the Mortal Kombat series
- JANET NRS Janet Name Registration Scheme
- NRS social grade and the National Readership Survey
- NRS process used for sugar thin-juice decalification in beet sugar factories
- NRS National Retail Systems Inc., Global Logistics and Trucking
- Non-rocket spacelaunch
- The National Runaway Switchboard, a national US hotline for youth in crisis.
- Nevada Revised Statutes Nevada laws
- Numerical Rating Scale for pain
- Norman-Roberts syndrome, a brain disorder
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