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NS2 may refer to:
- ns (simulator), computer network simulation software
- Natural Selection 2, a video game
- Nord Stream 2, a controversial proposed extension to the Nord Stream gas pipeline between Russia and Germany
- NS2 (HCV), a viral protein in the hepatitis C virus
- New Shepard 2, a reusable space launch vehicle
| disambiguation page lists articles associated with the same title formed as a letter-number combination.
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