Nicholas R. Cozzarelli

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Nicholas R. Cozzarelli
Born (1938-03-26)March 26, 1938
Jersey City, New Jersey
Died March 19, 2006(2006-03-19) (aged 67)
Nationality American
Fields Biochemistry
Institutions University of California, Berkeley
Alma mater Princeton University
Harvard Medical School
Thesis The L-L-Glycerophosphate Regulon in Escherichia coli (1966)
Academic advisors Arthur Kornberg
Doctoral students Patrick O. Brown
Known for Discovery of topoisomerases

Nicholas Robert Cozzarelli (March 26, 1938, in Jersey City, New Jersey – March 19, 2006) was an American biochemist at the University of California, Berkeley,[1] and former Editor-in-Chief of Proceedings of the National Academy of Sciences.


Cozzarelli attended Princeton University graduated with an A.B. in biology in 1960. He started graduate training at Harvard Medical School advised by E. C. C. Lin and earned a Ph.D. in biochemistry in 1966. He then did his postdoctoral training with Arthur Kornberg and purified the T4-phage DNA ligase.[2]


From 1968 to 1982, Cozzarelli was a professor at the University of Chicago where he studied topoisomerases. In 1982 he joined the faculty at University of California, Berkeley. He was elected to the National Academy of Sciences in 1989. In 1995, Cozzarelli was invited to become the editor-in-chief of the Proceedings of the National Academy of Sciences. He took the position because felt that the journal had great unrealized potential as a scientific publication.[3] During his tenure, he expanded the editorial board from 26 to more than 140 and created a second track to allow scientists to submit manuscripts directly.


Cozzarelli died on March 19, 2006, from the complications of treatment from Burkitt's lymphoma.


  1. ^ "IN MEMORIAM: Nicholas R. Cozzarelli". Retrieved 2012-05-25. 
  2. ^ Nuzzo, R.; Zagorski, N. (2006). "In Memoriam: PNAS Editor-in-Chief Nicholas R. Cozzarelli (1938-2006)". Proceedings of the National Academy of Sciences. 103 (16): 6078–6080. doi:10.1073/pnas.0602531103. PMC 1458831free to read. PMID 16595621. 
  3. ^ "Nicholas R. Cozzarelli dies". Retrieved 2012-05-25. 
Preceded by
Lawrence Bogorad
PNAS editor-in-chief
Succeeded by
Randy Schekman