Olfactomedin 1

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OLFM1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases OLFM1, AMY, NOE1, NOELIN1, OlfA, olfactomedin 1
External IDs MGI: 1860437 HomoloGene: 8612 GeneCards: OLFM1
Gene location (Human)
Chromosome 9 (human)
Chr. Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for OLFM1
Genomic location for OLFM1
Band 9q34.3 Start 135,075,422 bp[1]
End 135,121,179 bp[1]
RNA expression pattern
PBB GE OLFM1 210924 at fs.png

PBB GE OLFM1 205591 at fs.png

PBB GE OLFM1 213131 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_058199
NM_001282611
NM_001282612
NM_006334
NM_014279

NM_001038612
NM_001038613
NM_001038614
NM_019498

RefSeq (protein)

NP_001269540
NP_001269541
NP_006325
NP_055094

NP_001033701
NP_001033702
NP_001033703
NP_062371

Location (UCSC) Chr 9: 135.08 – 135.12 Mb Chr 9: 28.19 – 28.23 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactomedin 1, also known as noelin 1 or pancortin, is a protein that in humans is encoded by the OLFM1 gene.[5][6] The name noelin stands for "neuronal olfactomedin-related endoplasmic reticulum-localized 1".[7]

This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130558 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026833 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Yokoyama M, Nishi Y, Yoshii J, Okubo K, Matsubara K (May 1997). "Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles". DNA Res. 3 (5): 311–20. PMID 9039501. doi:10.1093/dnares/3.5.311. 
  6. ^ a b "Entrez Gene: OLFM1 olfactomedin 1". 
  7. ^ Anholt, Robert R. H. (2014). "Olfactomedin proteins: central players in development and disease". Frontiers in Cell and Developmental Biology. 2: 6. doi:10.3389/fcell.2014.00006. 

Further reading[edit]