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OSBPL9

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OSBPL9
Identifiers
AliasesOSBPL9, ORP-9, ORP9, oxysterol binding protein like 9
External IDsOMIM: 606737; MGI: 1923784; HomoloGene: 69380; GeneCards: OSBPL9; OMA:OSBPL9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 1: 51.58 – 51.8 MbChr 4: 109.06 – 109.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Oxysterol binding protein-like 9 is a protein that in humans is encoded by the OSBPL9 gene.[5]

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000117859Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028559Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: oxysterol binding protein-like 9". Retrieved 2011-08-30.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.