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Octavia may refer to:


  • Octavia the Elder, elder half sister of Octavia Minor
  • Octavia the Younger, sister of Augustus, younger half sister of Octavia Major and fourth wife of Mark Antony
  • Claudia Octavia, the daughter of Claudius and Valeria Messalina and first wife of Nero
  • Octahvia, American vocalist
  • Octavia E. Butler, African-American science fiction writer (1947-2006)
  • Octavia, the name taken by Mabel Barltrop of the Panacea Society in 1918
  • Octavia Spencer, African-American actress best known for her Academy Award-winning portrayal of Minnie, the outspoken maid, in the 2011 film The Help.