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Protein kinase C and casein kinase substrate in neurons 2
Protein PACSIN2 PDB 3ABH.png
Rendering based on PDB 3ABH.
Available structures
PDB Ortholog search: PDBe, RCSB
External IDs OMIM604960 MGI1345153 HomoloGene21414 GeneCards: PACSIN2 Gene
RNA expression pattern
PBB GE PACSIN2 201651 s at tn.png
More reference expression data
Species Human Mouse
Entrez 11252 23970
Ensembl ENSG00000100266 ENSMUSG00000016664
UniProt Q9UNF0 Q9WVE8
RefSeq (mRNA) NM_001184970 NM_001159509
RefSeq (protein) NP_001171899 NP_001152981
Location (UCSC) Chr 22:
43.23 – 43.41 Mb
Chr 15:
83.38 – 83.46 Mb
PubMed search [1] [2]

Protein kinase C and casein kinase substrate in neurons protein 2 is a protein that in humans is encoded by the PACSIN2 gene.[1][2][3]


PACSIN2 has been shown to interact with:


  1. ^ Ritter B, Modregger J, Paulsson M, Plomann M (Aug 1999). "PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins". FEBS Lett 454 (3): 356–62. doi:10.1016/S0014-5793(99)00830-3. PMID 10431838. 
  2. ^ a b c Modregger J, Ritter B, Witter B, Paulsson M, Plomann M (Jan 2001). "All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis". J Cell Sci. 113 Pt 24: 4511–21. PMID 11082044. 
  3. ^ "Entrez Gene: PACSIN2 protein kinase C and casein kinase substrate in neurons 2". 
  4. ^ Ghadimi MP, Sanzenbacher R, Thiede B, Wenzel J, Jing Q, Plomann M et al. (May 2002). "Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178)". FEBS Lett. 519 (1-3): 50–8. doi:10.1016/s0014-5793(02)02709-6. PMID 12023017. 
  5. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]