PANK4

PANK4
Identifiers
Aliases	PANK4, pantothenate kinase 4, pantothenate kinase 4 (inactive), CTRCT49
External IDs	OMIM: 606162; MGI: 2387466; HomoloGene: 41235; GeneCards: PANK4; OMA:PANK4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	2,526,597 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	155,065,395 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right hemisphere of cerebellum; ; blood; ; granulocyte; ; gastrocnemius muscle; ; skeletal muscle tissue; ; left ventricle; ; right auricle; ; muscle of thigh; ; pituitary gland;
	Top expressed in
	neural layer of retina; ; interventricular septum; ; extraocular muscle; ; otic vesicle; ; digastric muscle; ; vastus lateralis muscle; ; soleus muscle; ; temporal muscle; ; retinal pigment epithelium; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; pantothenate kinase activity; ATP binding; kinase activity;
Cellular component	cytoplasm;
Biological process	coenzyme A biosynthetic process; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	55229
	269614
	ENSG00000157881; ENSG00000273494
	ENSMUSG00000029056
	Q9NVE7
	Q80YV4
	NM_018216
	NM_172990; NM_001305804
	NP_060686
NP_001292733; NP_766578; NP_001392980; NP_001392981; NP_001392982;
	NP_001392983; NP_001392984; NP_001392985
	Wikidata
View/Edit Human	View/Edit Mouse

Pantothenate kinase 4 is an enzyme (pantothenate kinase) that in humans is encoded by the PANK4 gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000273494 GRCh38: Ensembl release 89: ENSG00000157881, ENSG00000273494 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029056 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhou B, Westaway SK, Levinson B, Johnson MA, Gitschier J, Hayflick SJ (Jul 2001). "A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome". Nat Genet. 28 (4): 345–9. doi:10.1038/ng572. PMID 11479594.
^ "Entrez Gene: PANK4 pantothenate kinase 4".