Phosphatidylethanolamine binding protein 1

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Protein PEBP1 PDB 1a44.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases PEBP1, HCNP, HCNPpp, HEL-210, HEL-S-34, PBP, PEBP, PEBP-1, RKIP, HEL-S-96, Phosphatidylethanolamine binding protein 1
External IDs MGI: 1344408 HomoloGene: 37637 GeneCards: PEBP1
Gene location (Human)
Chromosome 12 (human)
Chr. Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for PEBP1
Genomic location for PEBP1
Band 12q24.23 Start 118,135,858 bp[1]
End 118,145,584 bp[1]
RNA expression pattern
PBB GE PEBP1 210825 s at fs.png

PBB GE PEBP1 205353 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 12: 118.14 – 118.15 Mb Chr 5: 117.28 – 117.29 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene.[5][6]


Phosphatidylethanolamine binding protein 1 has been shown to interact with:


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089220 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032959 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Park S, Yeung ML, Beach S, Shields JM, Yeung KC (May 2005). "RKIP downregulates B-Raf kinase activity in melanoma cancer cells". Oncogene. 24 (21): 3535–40. doi:10.1038/sj.onc.1208435. PMID 15782137. 
  6. ^ "Entrez Gene: PEBP1 phosphatidylethanolamine binding protein 1". 
  7. ^ a b c Yeung K, Janosch P, McFerran B, Rose DW, Mischak H, Sedivy JM, Kolch W (May 2000). "Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein". Mol. Cell. Biol. 20 (9): 3079–85. doi:10.1128/mcb.20.9.3079-3085.2000. PMC 85596Freely accessible. PMID 10757792. 

Further reading[edit]