PEG 400

Polyethylene glycol
Names
	IUPAC name Polyethylene glycol
Identifiers
CAS Number	25322-68-3 ;
ChemSpider	none;
Properties
Chemical formula	C2nH4n+2On+1, n = 8.2 to 9.1
Molar mass	380-420 g/mol
Density	1.128 g/cm3
Melting point	4 to 8 °C (39 to 46 °F; 277 to 281 K)
Viscosity	90.0 cSt at 25 °C, 7.3 cSt at 99 °C
Hazards
Flash point	238 °C (460 °F; 511 K)
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	30 mL/kg, orally in rats
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

PEG 400 (polyethylene glycol 400) is a low-molecular-weight grade of polyethylene glycol. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.

Chemical properties

PEG 400 is strongly hydrophilic. The partition coefficient of PEG 400 between hexane and water is 0.000015 (log $P=-4.8$ ), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of PEG 400 in the hexane layer per 1 million parts of PEG 400 in the water layer.^[1]

PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons, and is slightly soluble in aliphatic hydrocarbons.

References

^ T. Y. Ma, D. Hollander, P. Krugliak, K. Katz (1990). "PEG 400, a hydrophilic molecular probe for measuring intestinal permeability". Gastroenterology. 98 (1): 39–46. PMID 2293598.{{cite journal}}: CS1 maint: multiple names: authors list (link)

The Merck Index, 11th Edition
Handbook of Pharmaceutical Excipients

[1] T. Y. Ma, D. Hollander, P. Krugliak, K. Katz (1990). "PEG 400, a hydrophilic molecular probe for measuring intestinal permeability". Gastroenterology. 98 (1): 39–46. PMID 2293598.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[1]