PELO

PELO
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X52
Identifiers
Aliases	PELO, PRO1770, CGI-17, pelota homolog (Drosophila), pelota mRNA surveillance and ribosome rescue factor
External IDs	OMIM: 605757; MGI: 2145154; HomoloGene: 6835; GeneCards: PELO; OMA:PELO - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	52,804,044 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	115,226,722 bp
RNA expression pattern
	Top expressed in
	vena cava; ; decidua; ; saphenous vein; ; cartilage tissue; ; tendon of biceps brachii; ; left adrenal gland; ; right adrenal cortex; ; stromal cell of endometrium; ; left adrenal cortex; ; oocyte;
	Top expressed in
	urethra; ; muscle layer of urethra; ; bone marrow; ; vagina; ; yolk sac; ; epithelium of urethra; ; lamina propria of urethra; ; epithelium of female urethra; ; epiblast; ; placenta;
	More reference expression data
	n/a
Gene ontology
Molecular function	endonuclease activity; nuclease activity; hydrolase activity; metal ion binding; protein binding; ribosome binding;
Cellular component	nucleus; cytoplasm;
Biological process	cell cycle; RNA surveillance; cell population proliferation; nuclear-transcribed mRNA catabolic process, non-stop decay; chromosome organization; nucleic acid phosphodiester bond hydrolysis; cell division; protein biosynthesis; endoderm development; stem cell population maintenance; positive regulation of BMP signaling pathway; ribosome disassembly; mesenchymal to epithelial transition; nonfunctional rRNA decay; nuclear-transcribed mRNA catabolic process, no-go decay; inner cell mass cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	53918
	105083
	ENSG00000152684
	ENSMUSG00000042275
	Q9BRX2
	Q80X73
	NM_015946
	NM_134058
	NP_057030
	NP_598819
	Wikidata
View/Edit Human	View/Edit Mouse

Protein pelota homolog is a protein that in humans is encoded by the PELO gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000152684 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042275 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shamsadin R, Adham IM, von Beust G, Engel W (Nov 2000). "Molecular cloning, expression and chromosome location of the human pelota gene PELO". Cytogenet Cell Genet. 90 (1–2): 75–8. doi:10.1159/000015667. PMID 11060452.
^ "Entrez Gene: PELO pelota homolog (Drosophila)".

References

Further reading