PES1

PES1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EP8
Identifiers
Aliases	PES1, PES, pescadillo ribosomal biogenesis factor 1, NOP7
External IDs	OMIM: 605819; MGI: 1890613; HomoloGene: 5984; GeneCards: PES1; OMA:PES1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	30,607,083 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	3,930,004 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; body of pancreas; ; islet of Langerhans; ; skin of leg; ; mucosa of transverse colon; ; skin of abdomen; ; left testis; ; stromal cell of endometrium; ; body of stomach; ; right testis;
	Top expressed in
	interventricular septum; ; yolk sac; ; spermatocyte; ; ventricular zone; ; neural layer of retina; ; tail of embryo; ; spermatid; ; otic vesicle; ; embryo; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; ribonucleoprotein complex binding;
Cellular component	membrane; PeBoW complex; chromosome; nucleolus; condensed chromosome; nucleus; nucleoplasm; cytosol; preribosome, large subunit precursor;
Biological process	protein localization to organelle; ribosome biogenesis; regulation of cell cycle; nucleolus organization; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cell population proliferation; rRNA processing; maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal large subunit biogenesis;
	Sources:Amigo / QuickGO
Orthologs
	23481
	64934
	ENSG00000100029
	ENSMUSG00000020430
	O00541
	Q9EQ61
	NM_001243225; NM_001282327; NM_001282328; NM_014303
	NM_022889
	NP_001230154; NP_001269256; NP_001269257; NP_055118
	NP_075027
	Wikidata
View/Edit Human	View/Edit Mouse

Pescadillo homolog is a protein that in humans is encoded by the PES1 gene.^[5]^[6]^[7]^[8]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100029 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020430 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Allende ML, Amsterdam A, Becker T, Kawakami K, Gaiano N, Hopkins N (Jan 1997). "Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development". Genes Dev. 10 (24): 3141–55. doi:10.1101/gad.10.24.3141. PMID 8985183.
^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
^ Rohrmoser M, Holzel M, Grimm T, Malamoussi A, Harasim T, Orban M, Pfisterer I, Gruber-Eber A, Kremmer E, Eick D (May 2007). "Interdependence of Pes1, Bop1, and WDR12 Controls Nucleolar Localization and Assembly of the PeBoW Complex Required for Maturation of the 60S Ribosomal Subunit". Mol Cell Biol. 27 (10): 3682–94. doi:10.1128/MCB.00172-07. PMC 1899993. PMID 17353269.
^ "Entrez Gene: PES1 pescadillo homolog 1, containing BRCT domain (zebrafish)".

References

Further reading