POLDIP3

POLDIP3
Identifiers
Aliases	POLDIP3, PDIP46, SKAR, polymerase (DNA) delta interacting protein 3, DNA polymerase delta interacting protein 3, PDIP3
External IDs	OMIM: 611520; MGI: 1921076; HomoloGene: 13007; GeneCards: POLDIP3; OMA:POLDIP3 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	42,614,962 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	83,033,585 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; oocyte; ; right uterine tube; ; islet of Langerhans; ; cardia; ; body of stomach; ; canal of the cervix; ; fundus; ; right lobe of thyroid gland; ; lymph node;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; motor neuron; ; condyle; ; fossa; ; medial ganglionic eminence; ; ascending aorta; ; aortic valve; ; supraoptic nucleus; ; Paneth cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; RNA binding; protein-containing complex binding;
Cellular component	exon-exon junction complex; transcription export complex; nucleus; nuclear speck; cytoplasm; cytosol; nucleoplasm; cytoplasmic ribonucleoprotein granule;
Biological process	poly(A)+ mRNA export from nucleus; mRNA transport; regulation of translation; positive regulation of translation; termination of RNA polymerase II transcription; mRNA 3'-end processing; RNA export from nucleus; mRNA export from nucleus; transport;
	Sources:Amigo / QuickGO
Orthologs
	84271
	73826
	ENSG00000100227
	ENSMUSG00000041815
	Q9BY77; Q8WUT1
	Q8BG81
	NM_001278657; NM_032311; NM_178136; NM_001363052
	NM_178627; NM_001347082
	NP_001265586; NP_115687; NP_835237; NP_001349981
	NP_001334011; NP_848742
	Wikidata
View/Edit Human	View/Edit Mouse

Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the POLDIP3 gene.^[5]^[6]

Template:PBB Summary

Interactions

POLDIP3 has been shown to interact with P70-S6 Kinase 1.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100227 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041815 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Liu L, Rodriguez-Belmonte EM, Mazloum N, Xie B, Lee MY (Mar 2003). "Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen". J Biol Chem. 278 (12): 10041–7. doi:10.1074/jbc.M208694200. PMID 12522211.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: POLDIP3 polymerase (DNA-directed), delta interacting protein 3".
^ Richardson, Celeste J; Bröenstrup Mark; Fingar Diane C; Jülich Kristina; Ballif Bryan A; Gygi Steven; Blenis John (Sep 2004). "SKAR is a specific target of S6 kinase 1 in cell growth control". Curr. Biol. 14 (17). England: 1540–9. doi:10.1016/j.cub.2004.08.061. ISSN 0960-9822. PMID 15341740. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading