POLR2J2

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POLR2J2
Identifiers
Aliases POLR2J2, polymerase (RNA) II (DNA directed) polypeptide J2, HRPB11B, RPB11b1, polymerase (RNA) II subunit J2, RNA polymerase II subunit J2
External IDs HomoloGene: 129653 GeneCards: POLR2J2
RNA expression pattern
PBB GE POLR2J2 216242 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_145325
NM_032958
NM_032959

n/a

RefSeq (protein)

NP_116581

n/a

Location (UCSC) Chr 7: 102.67 – 102.67 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

DNA directed RNA polymerase II polypeptide J-related gene, also known as POLR2J2, is a human gene.[2]

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.[2]

References[edit]

Further reading[edit]