Padmanabha may refer to:
- Padmanābha (poet), an Indian poet from the 15th century
- Padmanabhapuram, a town in Kanyakumari district, Tamil Nadu, India
- Anantha Padmanabha Swamy Temple, in Vikarabad, Andhra Pradesh, India
- Padmanabha Nagar, a neighborhood in Bangalore, Karnataka, India
- Padmanabha, in the Jain tradition, the future reincarnation of Bimbisara, King of Magadha
- Padmanabha, a manifestation of the Hindu god Vishnu with a lotus issuing from his navel
- Padmanabha Swamy, the presiding deity at the Padmanabhaswamy Temple in Thiruvananthapuram, Kerala, India
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