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Patchoulol synthase

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Patchoulol synthase
Identifiers
EC no.4.2.3.70
Databases
IntEnzIntEnz view
BRENDABRENDA entry
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Patchoulol synthase (EC 4.2.3.70) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming).[1][2][3] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O patchoulol + diphosphate

References

  1. ^ Croteau, R., Munck, S.L., Akoh, C.C., Fisk, H.J. and Satterwhite, D.M. (1987). "Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations". Arch. Biochem. Biophys. 256: 56–68. doi:10.1016/0003-9861(87)90425-5. PMID 3038029.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Munck, S.L. and Croteau, R. (1990). "Purification and characterization of the sesquiterpene cyclase patchoulol synthase from Pogostemon cablin". Arch. Biochem. Biophys. 282: 58–64. doi:10.1016/0003-9861(90)90086-e. PMID 2171435.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Faraldos, J.A., Wu, S., Chappell, J. and Coates, R.M. (2010). "Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-2H1]farnesyl diphosphate catalyzed by recombinant patchoulol synthase". J. Am. Chem. Soc. 132: 2998–3008. doi:10.1021/ja909251r. PMID 20148554.{{cite journal}}: CS1 maint: multiple names: authors list (link)