Sella turcica and pituitary gland.
|Anatomical terms of bone|
The sella turcica (Latin for Turkish seat) is a saddle-shaped depression in the body of the sphenoid bone of the human skull and of the skulls of other hominids including chimpanzees, orangutans, and gorillas. It serves as a cephalometric landmark. The seat of the saddle, the deepest part of the sella turcica known as the hypophyseal fossa, holds the pituitary gland (hypophysis).
The seat of the saddle, the deepest part of the sella turcica known as the hypophyseal fossa holds the pituitary gland (hypophysis). The sella turcica is located in the sphenoid bone behind the chiasmatic groove and the tuberculum sellae. It belongs to the middle cranial fossa. In front of the hypophyseal fossa is the tuberculum sellae.
Completing the formation of the saddle posteriorly is the dorsum sellae, which is continuous with the clivus, inferoposteriorly. The dorsum sellae is terminated laterally by the posterior clinoid processes.
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The sella turcica forms a bony seat for the pituitary gland.
Empty sella syndrome is the condition of a shrunken or flattened pituitary gland.
Since the sella turcica forms a bony caudal border for the pituitary gland, a pituitary tumor usually extends upward in the rostral direction into the suprasellar region. This can result in compression of the optic chiasm, which lies on top of the pituitary, enveloping the pituitary stalk. Compression of the optic chiasm can lead to bitemporal hemianopsia, and, when there is no relevant trauma, this clinical finding is pathognomonic for a pituitary tumor.
Some pituitary adenomas can extend inferiorly, growing downward and invading the sphenoid bone and cavernous sinus. Adenomas greater than 10mm (macroadenomas) can cause remodeling of the underlying sphenoid bone altering the shape of the sella turcica.
Based on this formation’s resemblance to a type of saddle with a broad seat, high pommel and cantle, the term was introduced to the anatomical nomenclature by the Flemish anatomist, physician, and botanist Adrianus Spigelius (1578−1625) in De Humani Corporis Fabrica (1627). In subsequent centuries, many books, especially medical dictionaries, included entries for sella turcica or its literary equivalent in different languages.
Sphenoid bone seen from above. Sella turcica shown in red.
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- Knosp E, Steiner E, Kitz K, et al. Pituitary adenomas with invasion of the cavernous sinus space: a magnetic resonance imaging classification compared with surgical findings. Neurosurgery. 1993 Oct;33(4):610-7; discussion 617-8. PMID 8232800
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- Tekiner, Halil; Acer, Niyazi; Kelestimur, Fahrettin (2014-10-12). "Sella turcica: an anatomical, endocrinological, and historical perspective". Pituitary. 18 (4): 575–578. doi:10.1007/s11102-014-0609-2. ISSN 1386-341X.
- Marieb, Elaine Nicpon (2004). Human Anatomy & Physiology (6th ed.). Pearson Education. p. 209. ISBN 0-8053-5462-X.
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