The Arizona sycamore is a tree of central Arizona's transition zone in the Mogollon Rim–White Mountains. The range extends into southwest New Mexico and parts of Sonora, Chihuahua, and Sinaloa in Mexico. In Arizona the range extends south towards northern Sonora. The range in southeast Arizona is a northeasterly part of the Sonoran Desert, and is at the northern region of the Sierra Madre Occidental cordillera.
Arizona sycamore is prevalent in riparian areas of the Madrean Sky Islands, mountain sky islands in southeast Arizona, extreme southwest, Bootheel region of New Mexico and along the San Francisco River in Western New Mexico, northeastern Sonora, and extreme northwest Chihuahua). The species is more prevalent west of the Madrean Sky Islands region, still in the central and northeast Sonoran Desert, an area around the Organ Pipe Cactus National Monument at the Arizona-Sonora border, with the species range extending in Sonora in the Occidentals, or its western foothills. Scattered reports have been made farther east in the Sierra Madre Occidental.
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