Pogosta disease

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Pogosta disease
Karelian fever
Ockelbo disease
Classification and external resources
Specialty infectious disease
ICD-10 A92.8[1]

Pogosta disease is a viral disease, established to be identical with other diseases, Karelian fever and Ockelbo disease.[2][3] The names are derived from the words Pogosta, Karelia and Ockelbo, respectively.

The symptoms of the disease include usually rash, as well as mild fever and other flu-like symptoms; in most cases the symptoms last less than 5 days. However, in some cases, the patients develop a painful arthritis. There are no known chemical agents available to treat the disease.[4]

It has long been suspected that the disease is caused by a Sindbis-like virus, a positive-stranded RNA virus belonging to the Alphavirus genus and family Togaviridae.[2] In 2002 a strain of Sindbis was isolated from patients during an outbreak of the Pogosta disease in Finland, confirming the hypothesis.[4]

This disease is mainly found in the Eastern parts of Finland; a typical Pogosta disease patient is a middle-aged person who has been infected through a mosquito bite while picking berries in the autumn. The prevalence of the disease is about 100 diagnosed cases every year, with larger outbreaks occurring in 7-year intervals.[4]

References[edit]

  1. ^ "Internetmedicin: Ockelbosjukan". Retrieved March 19, 2015. 
  2. ^ a b Lvov, D. K.; Vladimirtseva, E. A.; Butenko, A. M.; Karabatsos, N.; Trent, D. W.; Calisher, C. H. (1988). "Identity of Karelian fever and Ockelbo viruses determined by serum dilution-plaque reduction neutralization tests and oligonucleotide mapping". The American journal of tropical medicine and hygiene. 39 (6): 607–610. PMID 2849885. 
  3. ^ Laine, Maria (2002). Pogosta Disease. University of Turku. ISBN 951-29-2129-4. 
  4. ^ a b c Kurkela S, Manni T, Vaheri A, Vapalahti O (May 2004). "Causative agent of Pogosta disease isolated from blood and skin lesions". Emerg Infect Dis. 10 (5). doi:10.3201/eid1005.030689.