RAB11FIP5

RAB11FIP5
Identifiers
Aliases	RAB11FIP5, GAF1, RIP11, pp75, RAB11 family interacting protein 5, rab11-FIP5, gaf-1
External IDs	OMIM: 605536; MGI: 1098586; HomoloGene: 9158; GeneCards: RAB11FIP5; OMA:RAB11FIP5 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	73,156,721 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	85,351,616 bp
RNA expression pattern
	Top expressed in
	sperm; ; left testis; ; right testis; ; renal medulla; ; pons; ; spinal ganglia; ; lateral nuclear group of thalamus; ; human kidney; ; cartilage tissue; ; parotid gland;
	Top expressed in
	spermatid; ; testicle; ; spermatocyte; ; urinary bladder; ; cerebellar cortex; ; human kidney; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; hypothalamus; ; heart;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; gamma-tubulin binding;
Cellular component	cytoplasm; endosome; Golgi apparatus; early endosome membrane; intracellular membrane-bounded organelle; membrane; mitochondrial membranes; Golgi membrane; transport vesicle membrane; microtubule organizing center; mitochondrial outer membrane; recycling endosome membrane; mitochondrion; cytoplasmic vesicle; early endosome; secretory granule; recycling endosome;
Biological process	regulation of protein localization to cell surface; cellular response to acidic pH; protein transport; negative regulation of adiponectin secretion; insulin secretion involved in cellular response to glucose stimulus; regulated exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	26056
	52055
	ENSG00000135631
	ENSMUSG00000051343
	Q9BXF6
	Q8R361
	NM_015470; NM_001371272
	NM_001003955; NM_177466
	NP_056285; NP_001358201
	NP_001003955; NP_803417
	Wikidata
View/Edit Human	View/Edit Mouse

Rab11 family-interacting protein 5 is a protein that in humans is encoded by the RAB11FIP5 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

RAB11FIP5 has been shown to interact with RAB11A^[6]^[8]^[9] and RAB25.^[8]^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135631 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051343 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
^ ^a ^b Prekeris R, Klumperman J, Scheller RH (February 2001). "A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes". Mol Cell. 6 (6): 1437–48. doi:10.1016/S1097-2765(00)00140-4. PMID 11163216.
^ "Entrez Gene: RAB11FIP5 RAB11 family interacting protein 5 (class I)".
^ ^a ^b Hales, C M; Griner R; Hobdy-Henderson K C; Dorn M C; Hardy D; Kumar R; Navarre J; Chan E K; Lapierre L A; Goldenring J R (October 2001). "Identification and characterization of a family of Rab11-interacting proteins". J. Biol. Chem. 276 (42). United States: 39067–75. doi:10.1074/jbc.M104831200. ISSN 0021-9258. PMID 11495908. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)
^ ^a ^b Prekeris, R; Davies J M; Scheller R H (October 2001). "Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins". J. Biol. Chem. 276 (42). United States: 38966–70. doi:10.1074/jbc.M106133200. ISSN 0021-9258. PMID 11481332. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading