RCE1

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RCE1
Identifiers
AliasesRCE1, FACE2, RCE1A, RCE1B, Ras converting CAAX endopeptidase 1
External IDsMGI: 1336895 HomoloGene: 3769 GeneCards: RCE1
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for RCE1
Genomic location for RCE1
Band11q13.2Start66,842,835 bp[1]
End66,846,546 bp[1]
RNA expression pattern
PBB GE RCE1 205333 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005133
NM_001032279

NM_023131

RefSeq (protein)

NP_001027450
NP_005124

NP_075620

Location (UCSC)Chr 11: 66.84 – 66.85 MbChr 19: 4.62 – 4.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CAAX prenyl protease 2 is an enzyme that in humans is encoded by the RCE1 gene.[5][6][7]

This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173653 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024889 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Otto JC, Kim E, Young SG, Casey PJ (Apr 1999). "Cloning and characterization of a mammalian prenyl protein-specific protease". J Biol Chem. 274 (13): 8379–82. doi:10.1074/jbc.274.13.8379. PMID 10085068.
  6. ^ Freije JM, Blay P, Pendas AM, Cadinanos J, Crespo P, Lopez-Otin C (Jul 1999). "Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins". Genomics. 58 (3): 270–80. doi:10.1006/geno.1999.5834. PMID 10373325.
  7. ^ a b "Entrez Gene: RCE1 RCE1 homolog, prenyl protein peptidase (S. cerevisiae)".

Further reading[edit]