Leonard was born in London; she went to the girls' grammar school Dr Challoner's High School in Little Chalfont. She then went to the all-female Newnham College, Cambridge where she graduated with double first-class honours, before completing her training at St Thomas's Hospital Medical School.
She has written for national newspapers and magazines, including Hello!, The Sun, the Daily Mail and the Daily Express since 1986. She has been the resident GP for BBC Breakfast News since 1998.
Leonard has two sons.
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