Geronemus has contributed to the clinical development of laser and technology systems for devices for the treament of skin problems including the pulsed dye laser, q-switched ruby laser, q-switched Nd:YAG laser, Ultrapulse carbon dioxide laser, Silktouch carbon dioxide laser, KTP laser, Thermage radiofrequency, light emitting diodes, non-ablative and ablative fractional resurfacing lasers, and the Picosecond laser. His publications have covered treatments for port wine stains,hemangiomas, sun damaged skin, wrinkles, telangiectases, birthmarks, skin laxity, hair removal, tattoo removal and Nevus of Ota removal. Geronemus has advocated the early intervention of vascular birthmarks, encouraging treatment during early infancy 
^ abKauvar A, Geronemus R. "Pulsed dye laser therapy of resistant port-wine stains." Dermatol Surg.1995;21:515-21.
^ abBrauer JA, Reddy KK, Anolik R, Weiss ET, Karen JK, Hale EK, Brightman LA, Bernstein L, Geronemus RG. "Successful and rapid treatment of blue and green tattoo pigment with a novel picosecond laser." Arch Dermatol. 2012 Jul;148(7):820-3.
^Lou W, Geronemus R. "Treatment of port-wine stains by variable pulse width pulsed dye laser with cryogen spray: a preliminary study." Dermatol Surg.2001;27:963-5
^Geronemus R, Lou W, Quintana A, Kauvar A. "High fluence modified pulsed dye laser photocoagulation with dynamic cooling of port wine stains in infancy." Arch Dermatol.2000;136:942-3.
^Reddy KK, Blei F, Brauer JA, Waner M, Berstein L, Brightman LA, Hale EK, Karen JK, Weiss ET, Geronemus RG. "Infantile hemangiomas treated with a combination of propranolol and pulsed dye laser." Lasers Surg Med.2012;44(S24):3-4.
^Geronemus RG, Hunzeker CM. "Letter regarding early laser treatment of periorbital infantile hemangiomas may work, but is it really the best treatment option?" Dermatol Surg. 2010; 36(9):1495-97.
^Geronemus RG. "Pulsed dye laser treatment of vascular lesions in children." J Dermatol Surg Oncol.1993 Apr;19(4):303-10.
^Waldorf HA, Kauvar AN, Geronemus RG. "Treatment of small and medium congenital nevi with the Q-switched ruby laser." Arch Dermatol.1996 Mar;132(3):301-4.
^Brightman LA, Brauer J, Geronemus RG, Karen J, Hale E, Bernstein L, Weiss ET, Anolik R, Reddy K. Abstract of “3-dimensional evaluation of a minimally invasive fractional bipolar radiofrequency device for lifting and volumizing of the face.” Lasers Surg Med. 2012; 44(S24):12-3.
^Brightman L, Weiss E, Chapas A, Karen J, Hale E, Bernstein L, Geronemus RG. “Improvement in arm and post-partum abdominal and flank subcutaneous fat deposits and skin laxity using a bipolar radiofrequency, infrared, vacuum and mechanical massage device.” Lasers Surg Med.2009;41:791-8.
^Landau JM, Vergilis-Kalner I, Goldberg LH, Geronemus RG, Friedman PM. "Treatment of Nevus of Ota in Fitzpatrick skin type VI with the 1064-nm QS Nd:YAG laser." Lasers Surg Med. 2011 Feb; 43(2):65-7.
^Geronemus RG. "Q-switched Ruby Laser Therapy of Nevus of Ota." Arch Dermatol. 1992 Dec; 128(12):1618-22.
^Chapas AM, Eickhorst K, Geronemus RG. “Efficacy of early treatment of facial port-wine stains in newborns: A review of 49 Cases.” Lasers Surg Med. 2007 Aug;39(7):563-8)