SEMA6A

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SEMA6A
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SEMA6A, HT018, SEMA, SEMA6A1, SEMAQ, VIA, semaphorin 6A
External IDs MGI: 1203727 HomoloGene: 32426 GeneCards: 57556
RNA expression pattern
PBB GE SEMA6A 220454 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300780
NM_020681
NM_020796

NM_018744
NM_001311097

RefSeq (protein)

NP_001287709.1
NP_065847.1

NP_001298026.1
NP_061214.2

Location (UCSC) Chr 5: 116.44 – 116.57 Mb Chr 18: 47.24 – 47.37 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Semaphorin-6A is a protein that in humans is encoded by the SEMA6A gene.[1][2][3]

In melanocytic cells SEMA6A gene expression may be regulated by MITF.[4]


References[edit]

  1. ^ Zhou L, White FA, Lentz SI, Wright DE, Fisher DA, Snider WD (Sep 1997). "Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I". Mol Cell Neurosci 9 (1): 26–41. doi:10.1006/mcne.1997.0607. PMID 9204478. 
  2. ^ Klostermann A, Lutz B, Gertler F, Behl C (Jan 2001). "The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain". J Biol Chem 275 (50): 39647–53. doi:10.1074/jbc.M006316200. PMID 10993894. 
  3. ^ "Entrez Gene: SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A". 
  4. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 

Further reading[edit]