SETD8

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KMT5A
Protein SETD8 PDB 1zkk.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KMT5A, PR-Set7, SET07, SET8, SETD8, lysine methyltransferase 5A
External IDs MGI: 1915206 HomoloGene: 41372 GeneCards: KMT5A
EC number 2.1.1.43
RNA expression pattern
PBB GE SETD8 220200 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020382
NM_001324504
NM_001324505
NM_001324506

NM_030241
NM_001310723
NM_001310725
NM_001310727

RefSeq (protein)

NP_001311433
NP_001311434
NP_001311435
NP_065115

Location (UCSC) Chr 12: 123.38 – 123.41 Mb Chr 5: 124.44 – 124.46 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Histone-lysine N-methyltransferase SETD8 is an enzyme that in humans is encoded by the SETD8 gene.[3][4][5][6]


References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Couture JF, Collazo E, Brunzelle JS, Trievel RC (Jun 2005). "Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase". Genes Dev. 19 (12): 1455–65. doi:10.1101/gad.1318405. PMC 1151662Freely accessible. PMID 15933070. 
  4. ^ Nishioka K, Rice JC, Sarma K, Erdjument-Bromage H, Werner J, Wang Y, Chuikov S, Valenzuela P, Tempst P, Steward R, Lis JT, Allis CD, Reinberg D (Jun 2002). "PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin". Mol Cell. 9 (6): 1201–13. doi:10.1016/S1097-2765(02)00548-8. PMID 12086618. 
  5. ^ Fang J, Feng Q, Ketel CS, Wang H, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Simon JA, Zhang Y (Jul 2002). "Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase". Curr Biol. 12 (13): 1086–99. doi:10.1016/S0960-9822(02)00924-7. PMID 12121615. 
  6. ^ "Entrez Gene: SETD8 SET domain containing (lysine methyltransferase) 8". 

Further reading[edit]

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