SH3GL1

SH3GL1
Identifiers
Aliases	SH3GL1, CNSA1, EEN, SH3D2B, SH3P8, SH3 domain containing GRB2 like 1, endophilin A2
External IDs	OMIM: 601768; MGI: 700010; HomoloGene: 55709; GeneCards: SH3GL1; OMA:SH3GL1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	4,400,547 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	56,343,635 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; mucosa of pharynx; ; ectocervix; ; stromal cell of endometrium; ; olfactory bulb; ; left adrenal cortex; ; right adrenal cortex; ; gastric mucosa; ; vagina;
	Top expressed in
	spermatocyte; ; granulocyte; ; lip; ; yolk sac; ; calvaria; ; spermatid; ; esophagus; ; neural tube; ; embryo; ; internal carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding; lipid binding; cadherin binding; SH3 domain binding; beta-1 adrenergic receptor binding; transmembrane transporter binding; protein C-terminus binding; phosphatase binding; GTPase binding;
Cellular component	cytoplasm; podosome; cell junction; endosome; cell projection; early endosome membrane; membrane; cytosol; hippocampal mossy fiber to CA3 synapse; synapse; Schaffer collateral - CA1 synapse; presynapse; glutamatergic synapse; postsynaptic density, intracellular component;
Biological process	central nervous system development; endocytosis; signal transduction; synaptic vesicle uncoating; modulation of excitatory postsynaptic potential; regulation of synaptic vesicle endocytosis; positive regulation of synaptic vesicle endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	6455
	20405
	ENSG00000141985
	ENSMUSG00000003200
	Q99961; Q6FGM0
	Q62419
	NM_001199943; NM_001199944; NM_003025
	NM_001252471; NM_013664; NM_001357649
	NP_001186872; NP_001186873; NP_003016; NP_003016.1
	NP_001239400; NP_038692; NP_001344578
	Wikidata
View/Edit Human	View/Edit Mouse

Endophilin-A2 is a protein that in humans is encoded by the SH3GL1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141985 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003200 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Giachino C, Lantelme E, Lanzetti L, Saccone S, Bella Valle G, Migone N (Jul 1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics. 41 (3): 427–34. doi:10.1006/geno.1997.4645. PMID 9169142.
^ "Entrez Gene: SH3GL1 SH3-domain GRB2-like 1".

References

Further reading