SLC27A5

SLC27A5
Identifiers
Aliases	SLC27A5, ACSB, ACSVL6, BACS, BAL, FACVL3, FATP-5, FATP5, VLACSR, VLCS-H2, VLCSH2, solute carrier family 27 member 5
External IDs	OMIM: 603314 MGI: 1347100 HomoloGene: 7596 GeneCards: SLC27A5
Gene location (Human)
Chr.	Chromosome 19 (human)
End	58,512,413 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	12,732,119 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; nucleus accumbens; ; amygdala; ; caudate nucleus; ; putamen; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; hypothalamus; ; substantia nigra;
	Top expressed in
	left lobe of liver; ; gallbladder; ; sexually immature organism; ; morula; ; yolk sac; ; duodenum; ; cerebellar cortex; ; thoracic diaphragm; ; skeletal muscle tissue; ; ureter;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; fatty acid transmembrane transporter activity; cholate-CoA ligase activity; ligase activity; catalytic activity; very long-chain fatty acid-CoA ligase activity; ATP binding; long-chain fatty acid-CoA ligase activity; protein-containing complex binding; long-chain fatty acid transporter activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; integral component of endoplasmic reticulum membrane; basal plasma membrane; endoplasmic reticulum; protein-containing complex;
Biological process	lipid metabolism; very long-chain fatty acid metabolic process; fatty acid transport; fatty acid metabolic process; ketone body biosynthetic process; bile acid and bile salt transport; long-chain fatty acid import across plasma membrane; metabolism; long-chain fatty acid metabolic process; bile acid biosynthetic process; triglyceride mobilization; bile acid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10998
	26459
	ENSG00000083807
	ENSMUSG00000030382
	Q9Y2P5
	Q4LDG0
	NM_012254; NM_001321196
	NM_009512
	NP_001308125; NP_036386
	NP_033538
	Wikidata
View/Edit Human	View/Edit Mouse

Bile acyl-CoA synthetase is an enzyme that in humans is encoded by the SLC27A5 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000083807 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030382 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Steinberg SJ, Wang SJ, McGuinness MC, Watkins PA (Oct 1999). "Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein". Mol Genet Metab. 68 (1): 32–42. doi:10.1006/mgme.1999.2883. PMID 10479480.
^ Steinberg SJ, Mihalik SJ, Kim DG, Cuebas DA, Watkins PA (Jun 2000). "The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase". J Biol Chem. 275 (21): 15605–8. doi:10.1074/jbc.C000015200. PMID 10749848.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: SLC27A5 solute carrier family 27 (fatty acid transporter), member 5".

SLC27A5

See also

References

Further reading