Sugar transporter SWEET1

SLC50A1
Identifiers
Aliases	SLC50A1, HsSWEET1, RAG1AP1, SCP, SWEET1, slv, solute carrier family 50 member 1
External IDs	OMIM: 613683; MGI: 107417; HomoloGene: 40647; GeneCards: SLC50A1; OMA:SLC50A1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q22 Start 155,135,344 bp End 155,138,857 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3 F1|3 39.04 cM Start 89,175,553 bp End 89,177,877 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon rectum body of pancreas right adrenal gland islet of Langerhans right adrenal cortex left adrenal gland right lobe of liver beta cell left adrenal cortex Top expressed in ankle joint primary visual cortex superior frontal gyrus Ileal epithelium lip islet of Langerhans carotid body epithelium of stomach right kidney parotid gland More reference expression data BioGPS n/a
Gene ontology Molecular function glucoside transmembrane transporter activity sugar transmembrane transporter activity Cellular component nucleus Golgi membrane membrane integral component of membrane Golgi apparatus endomembrane system plasma membrane Biological process carbohydrate transport epigenetic maintenance of chromatin in transcription-competent conformation glucoside transport hexose transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55974 19729 Ensembl ENSG00000169241 ENSMUSG00000027953 UniProt Q9BRV3 Q9CXK4 RefSeq (mRNA) NM_001122837 NM_001122839 NM_001287586 NM_001287587 NM_001287588 NM_001287589 NM_001287590 NM_001287591 NM_001287592 NM_018845 NM_009057 RefSeq (protein) NP_001116309 NP_001116311 NP_001274515 NP_001274516 NP_001274517 NP_001274518 NP_001274519 NP_001274520 NP_001274521 NP_061333 NP_033083 Location (UCSC) Chr 1: 155.14 – 155.14 Mb Chr 3: 89.18 – 89.18 Mb PubMed search
Wikidata
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The sugar transporter SWEET1, also known as solute carrier family 50 member 1, RAG1-activating protein 1 and stromal cell protein (SCP), is a membrane protein that in humans is encoded by the SLC50A1 gene.

Further reading

• Barnhill JC, Stokes AJ, Koblan-Huberson M, Shimoda LM, Muraguchi A, Adra CN, Turner H (Mar 2004). "RGA protein associates with a TRPV ion channel during biosynthesis and trafficking". Journal of Cellular Biochemistry. 91 (4): 808–20. doi:10.1002/jcb.10775. PMID 14991772.
• Pankratz N, Beecham GW, DeStefano AL, Dawson TM, Doheny KF, Factor SA, Hamza TH, Hung AY, Hyman BT, Ivinson AJ, Krainc D, Latourelle JC, Clark LN, Marder K, Martin ER, Mayeux R, Ross OA, Scherzer CR, Simon DK, Tanner C, Vance JM, Wszolek ZK, Zabetian CP, Myers RH, Payami H, Scott WK, Foroud T (Mar 2012). "Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2". Annals of Neurology. 71 (3): 370–84. doi:10.1002/ana.22687. PMC 3354734. PMID 22451204.
• Chen LQ, Hou BH, Lalonde S, Takanaga H, Hartung ML, Qu XQ, Guo WJ, Kim JG, Underwood W, Chaudhuri B, Chermak D, Antony G, White FF, Somerville SC, Mudgett MB, Frommer WB (Nov 2010). "Sugar transporters for intercellular exchange and nutrition of pathogens". Nature. 468 (7323): 527–32. doi:10.1038/nature09606. PMC 3000469. PMID 21107422.
• Tagoh H, Kishi H, Muraguchi A (Apr 1996). "Molecular cloning and characterization of a novel stromal cell-derived cDNA encoding a protein that facilitates gene activation of recombination activating gene (RAG)-1 in human lymphoid progenitors". Biochemical and Biophysical Research Communications. 221 (3): 744–9. doi:10.1006/bbrc.1996.0667. PMID 8630032.