SLURP1

SLURP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MUP, 2MUO
Identifiers
Aliases	SLURP1, ANUP, ARS, ArsB, LY6LS, MDM, secreted LY6/PLAUR domain containing 1, LY6-MT
External IDs	OMIM: 606119; MGI: 1930923; HomoloGene: 10710; GeneCards: SLURP1; OMA:SLURP1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	142,742,406 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	74,599,883 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; mucosa of pharynx; ; human penis; ; skin of arm; ; skin of abdomen; ; oral cavity; ; skin of thigh; ; body of tongue; ; vulva; ; gums;
	Top expressed in
	lip; ; skin of external ear; ; esophagus; ; pyloric antrum; ; mucous cell of stomach; ; cornea; ; cervix; ; ankle; ; spermatocyte; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; acetylcholine receptor activator activity; protein binding;
Cellular component	extracellular exosome; extracellular space; extracellular region;
Biological process	cell adhesion; negative regulation of keratinocyte proliferation; neuromuscular process controlling posture; locomotory behavior; cell activation; negative regulation of cell population proliferation; negative regulation of cell migration; urokinase plasminogen activator signaling pathway; positive regulation of signaling receptor activity; regulation of signaling receptor activity; regulation of neurotransmitter receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	57152
	57277
	ENSG00000126233
	ENSMUSG00000022596
	P55000
	Q9Z0K7
	NM_020427
	NM_020519
	NP_065160
	NP_065265
	Wikidata
View/Edit Human	View/Edit Mouse

Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000126233 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022596 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fischer J, Bouadjar B, Heilig R, Huber M, Lefevre C, Jobard F, Macari F, Bakija-Konsuo A, Ait-Belkacem F, Weissenbach J, Lathrop M, Hohl D, Prud'homme JF (Apr 2001). "Mutations in the gene encoding SLURP-1 in Mal de Meleda". Hum Mol Genet. 10 (8): 875–80. doi:10.1093/hmg/10.8.875. PMID 11285253.
^ Adermann K, Wattler F, Wattler S, Heine G, Meyer M, Forssmann WG, Nehls M (Jul 1999). "Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily". Protein Sci. 8 (4): 810–9. doi:10.1110/ps.8.4.810. PMC 2144295. PMID 10211827.
^ "Entrez Gene: SLURP1 secreted LY6/PLAUR domain containing 1".

References

Further reading