SMOX

SMOX
Identifiers
Aliases	SMOX, C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO, spermine oxidase
External IDs	OMIM: 615854; MGI: 2445356; HomoloGene: 69268; GeneCards: SMOX; OMA:SMOX - orthologs
EC number	1.5.3.16
Gene location (Human)
Chr.	Chromosome 20 (human)
End	4,187,747 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	131,525,922 bp
RNA expression pattern
	Top expressed in
	amygdala; ; C1 segment; ; putamen; ; substantia nigra; ; hypothalamus; ; nucleus accumbens; ; monocyte; ; cartilage tissue; ; caudate nucleus; ; Region I of hippocampus proper;
	Top expressed in
	triceps brachii muscle; ; sternocleidomastoid muscle; ; vastus lateralis muscle; ; knee joint; ; gastrocnemius muscle; ; granulocyte; ; medial head of gastrocnemius muscle; ; skeletal muscle tissue; ; fetal liver hematopoietic progenitor cell; ; molar;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity; polyamine oxidase activity; oxidoreductase activity; norspermine:oxygen oxidoreductase activity; spermine:oxygen oxidoreductase (spermidine-forming) activity;
Cellular component	cytosol; nucleus; cytoplasm; nucleoplasm; nuclear membrane; intracellular membrane-bounded organelle;
Biological process	polyamine catabolic process; spermine catabolic process; polyamine biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	54498
	228608
	ENSG00000088826
	ENSMUSG00000027333
	Q9NWM0
	Q99K82
NM_001270691; NM_175839; NM_175840; NM_175841; NM_175842;
	NM_019025
NM_001177833; NM_001177834; NM_001177835; NM_001177836; NM_001177837;
	NM_001177838; NM_001177839; NM_001177840; NM_145533
	NP_001257620; NP_787033; NP_787034; NP_787035; NP_787036
NP_001171304; NP_001171305; NP_001171306; NP_001171307; NP_001171308;
	NP_001171309; NP_001171310; NP_001171311; NP_663508
	Wikidata
View/Edit Human	View/Edit Mouse

Spermine oxidase is an enzyme that in humans is encoded by the SMOX gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000088826 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027333 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wang Y; Devereux W; Woster PM; Stewart TM; Hacker A; Casero RA Jr (Jul 2001). "Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure". Cancer Res. 61 (14): 5370–3. PMID 11454677.
^ Murray-Stewart T, Wang Y, Devereux W, Casero RA Jr (Dec 2002). "Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics". Biochem J. 368 (Pt 3): 673–7. doi:10.1042/BJ20021587. PMC 1223052. PMID 12398765.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ "Entrez Gene: SMOX spermine oxidase".

References

Further reading