STEAP2

STEAP2
Identifiers
Aliases	STEAP2, IPCA1, PCANAP1, PUMPCn, STAMP1, STMP, STEAP2 metalloreductase
External IDs	OMIM: 605094; MGI: 1921301; HomoloGene: 17682; GeneCards: STEAP2; OMA:STEAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	90,238,137 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	5,744,578 bp
RNA expression pattern
	Top expressed in
	pericardium; ; Achilles tendon; ; prostate; ; cardiac muscle tissue of right atrium; ; Brodmann area 23; ; middle temporal gyrus; ; pancreatic epithelial cell; ; cerebellar vermis; ; superior frontal gyrus; ; cartilage tissue;
	Top expressed in
	Epithelium of choroid plexus; ; endothelial cell of lymphatic vessel; ; oocyte; ; primary oocyte; ; secondary oocyte; ; lumbar subsegment of spinal cord; ; deep cerebellar nuclei; ; lobe of cerebellum; ; human kidney; ; olfactory epithelium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transporter activity; metal ion binding; cupric reductase activity; ferric-chelate reductase (NADPH) activity; oxidoreductase activity;
Cellular component	integral component of membrane; integral component of Golgi membrane; cytosol; endosome; membrane; plasma membrane; early endosome; trans-Golgi network transport vesicle; endosome membrane; integral component of plasma membrane;
Biological process	endocytosis; iron ion homeostasis; copper ion import; ion transport; response to hormone; regulated exocytosis; Golgi to plasma membrane transport; iron ion import across cell outer membrane;
	Sources:Amigo / QuickGO
Orthologs
	261729
	74051
	ENSG00000157214
	ENSMUSG00000015653
	Q8NFT2
	Q8BWB6
NM_001040665; NM_001040666; NM_001244944; NM_001244945; NM_001244946;
	NM_152999
NM_001103156; NM_001103157; NM_001285469; NM_001285470; NM_001285471;
	NM_028734
NP_001035755; NP_001035756; NP_001231873; NP_001231874; NP_001231875;
	NP_694544
NP_001096626; NP_001096627; NP_001272398; NP_001272399; NP_001272400;
	NP_083010
	Wikidata
View/Edit Human	View/Edit Mouse

Metalloreductase STEAP2 is an enzyme that in humans is encoded by the STEAP2 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000157214 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015653 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Walker MG, Volkmuth W, Sprinzak E, Hodgson D, Klingler T (Jan 2000). "Prediction of Gene Function by Genome-Scale Expression Analysis: Prostate Cancer-Associated Genes". Genome Res. 9 (12): 1198–203. doi:10.1101/gr.9.12.1198. PMC 310991. PMID 10613842.
^ Korkmaz KS, Elbi C, Korkmaz CG, Loda M, Hager GL, Saatcioglu F (Sep 2002). "Molecular cloning and characterization of STAMP1, a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer". J Biol Chem. 277 (39): 36689–96. doi:10.1074/jbc.M202414200. PMID 12095985.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: STEAP2 six transmembrane epithelial antigen of the prostate 2".

References

Further reading