STHS may refer to:
- St. Thomas High School (Houston, Texas), a high school for boys in Houston, Texas, USA
- Santa Teresa High School, a high school in San Jose, California, USA
- South Tahoe High School, a high school in South Lake Tahoe, California, USA
- South Terrebonne High School, a high school Bourg, Louisiana, USA
- Springfield Township High School, a high school in Oreland, Pennsylvania, USA
- Sydney Technical High School, a high school for boys in Sydney, New South Wales, Australia
- Saint Thomas Health Services, a not-for-profit group of Middle Tennessee hospitals based in Nashville, Tennessee, USA
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