SULT1C4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
SULT1C4
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases SULT1C4, SULT1C, SULT1C2, sulfotransferase family 1C member 4
External IDs HomoloGene: 41383 GeneCards: SULT1C4
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006588
NM_001321770

n/a

RefSeq (protein)

NP_001308699
NP_006579

n/a

Location (UCSC) Chr 2: 108.38 – 108.39 Mb n/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Sulfotransferase 1C4 is an enzyme that in humans is encoded by the SULT1C4 gene.[2][3][4]

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ Freimuth RR, Raftogianis RB, Wood TC, Moon E, Kim UJ, Xu J, Siciliano MJ, Weinshilboum RM (Jul 2000). "Human sulfotransferases SULT1C1 and SULT1C2: cDNA characterization, gene cloning, and chromosomal localization". Genomics. 65 (2): 157–65. doi:10.1006/geno.2000.6150. PMID 10783263. 
  3. ^ Sakakibara Y, Yanagisawa K, Katafuchi J, Ringer DP, Takami Y, Nakayama T, Suiko M, Liu MC (Jan 1999). "Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene". J Biol Chem. 273 (51): 33929–35. doi:10.1074/jbc.273.51.33929. PMID 9852044. 
  4. ^ a b "Entrez Gene: SULT1C2 sulfotransferase family, cytosolic, 1C, member 2". 

Further reading[edit]