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Smiles or SMILES may refer to:
- Samuel Smiles, Scottish author and reformer; biographer of engineers and author of Self-Help
- Tom Smiles, English professional footballer
- "Smiles", a 1917 song written by J. Will Callahan and Lee S. Roberts, from the Broadway revue The Passing Show of 1918
- Smiles (Hitomi Shimatani song) 2009 theme for the Japanese film Parallel
- Smiles (musical), a 1930 Broadway musical with music by Vincent Youmans
- Smiles, slang for recreational drug compounds believed to contain the hallucinogenic designer drug 2C-I
- Smiles S.A., the frequent flyer program of Gol Transportes Aéreos and Varig
- SMILES, Simplified molecular-input line-entry system, chemistry notation
|This disambiguation page lists articles associated with the title Smiles.
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