TMEFF2

TMEFF2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2FMW
Identifiers
Aliases	TMEFF2, CT120.2, HPP1, TENB2, TPEF, TR, TR-2, transmembrane protein with EGF like and two follistatin like domains 2
External IDs	OMIM: 605734; MGI: 1861735; HomoloGene: 9417; GeneCards: TMEFF2; OMA:TMEFF2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	192,194,933 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	51,226,429 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 46; ; spinal ganglia; ; Brodmann area 23; ; thalamus; ; pars reticulata; ; entorhinal cortex; ; corpus callosum; ; subthalamic nucleus; ; endothelial cell;
	Top expressed in
	anterior horn of spinal cord; ; facial motor nucleus; ; anterior amygdaloid area; ; supraoptic nucleus; ; optic nerve; ; habenula; ; lateral hypothalamus; ; ventral tegmental area; ; globus pallidus; ; deep cerebellar nuclei;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	integral component of membrane; extracellular region; membrane; plasma membrane;
Biological process	negative regulation of integrin biosynthetic process; negative regulation of cell migration; negative regulation of stress fiber assembly; wound healing, spreading of cells; animal organ morphogenesis; tissue development;
	Sources:Amigo / QuickGO
Orthologs
	23671
	56363
	ENSG00000144339
	ENSMUSG00000026109
	Q9UIK5
	Q9QYM9
	NM_001305134; NM_001305145; NM_016192
	NM_019790
	NP_001292063; NP_001292074; NP_057276
	NP_062764
	Wikidata
View/Edit Human	View/Edit Mouse

Tomoregulin-2 is a protein that in humans is encoded by the TMEFF2 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144339 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026109 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Horie M, Mitsumoto Y, Kyushiki H, Kanemoto N, Watanabe A, Taniguchi Y, Nishino N, Okamoto T, Kondo M, Mori T, Noguchi K, Nakamura Y, Takahashi E, Tanigami A (Aug 2000). "Identification and characterization of TMEFF2, a novel survival factor for hippocampal and mesencephalic neurons". Genomics. 67 (2): 146–52. doi:10.1006/geno.2000.6228. PMID 10903839.
^ "Entrez Gene: TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2".

References

Further reading