TRIP13

TRIP13
Identifiers
Aliases	TRIP13, 16E1BP, thyroid hormone receptor interactor 13, MVA3, OOMD9
External IDs	OMIM: 604507; MGI: 1916966; HomoloGene: 3125; GeneCards: TRIP13; OMA:TRIP13 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	919,357 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	74,085,903 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; oocyte; ; gonad; ; secondary oocyte; ; right testis; ; left testis; ; ventricular zone; ; mucosa of paranasal sinus; ; sperm; ; testicle;
	Top expressed in
	otic placode; ; primitive streak; ; abdominal wall; ; endothelial cell of lymphatic vessel; ; Paneth cell; ; endocardial cushion; ; saccule; ; condyle; ; somite; ; otic vesicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; transcription coregulator activity; ATP binding; identical protein binding;
Cellular component	male germ cell nucleus; nucleus; chromosome;
Biological process	meiosis; reciprocal meiotic recombination; male meiosis I; cell differentiation; oocyte maturation; double-strand break repair; transcription by RNA polymerase II; synaptonemal complex assembly; spermatogenesis; female meiosis I; spermatid development; oogenesis; mitotic spindle assembly checkpoint signaling; regulation of nucleic acid-templated transcription; meiotic recombination checkpoint signaling;
	Sources:Amigo / QuickGO
Orthologs
	9319
	69716
	ENSG00000071539
	ENSMUSG00000021569
	Q15645
	Q3UA06
	NM_001166260; NM_004237
	NM_027182
	NP_001159732; NP_004228
	NP_081458
	Wikidata
View/Edit Human	View/Edit Mouse

Thyroid receptor-interacting protein 13 is a protein that in humans is encoded by the TRIP13 gene.^[5]^[6]

Interactions

TRIP13 has been shown to interact with MAD2L1BP.^[7]^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000071539 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021569 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (Feb 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Molecular Endocrinology. 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974.
^ "Entrez Gene: TRIP13 thyroid hormone receptor interactor 13".
^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
^ Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.

Schepens J, Cuppen E, Wieringa B, Hendriks W (Jun 1997). "The neuronal nitric oxide synthase PDZ motif binds to -G(D,E)XV* carboxyterminal sequences". FEBS Letters. 409 (1): 53–6. doi:10.1016/S0014-5793(97)00481-X. PMID 9199503.
Yasugi T, Vidal M, Sakai H, Howley PM, Benson JD (Aug 1997). "Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins". Journal of Virology. 71 (8): 5942–51. PMC 191850. PMID 9223484.
Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S, Bono H, Okazaki Y, Hayashizaki Y (Oct 2001). "Protein-protein interaction panel using mouse full-length cDNAs". Genome Research. 11 (10): 1758–65. doi:10.1101/gr.180101. PMC 311163. PMID 11591653.
Kim HJ, Chong KH, Kang SW, Lee JR, Kim JY, Hahn MJ, Kim TJ (Sep 2004). "Identification of cyclophilin A as a CD99-binding protein by yeast two-hybrid screening". Immunology Letters. 95 (2): 155–9. doi:10.1016/j.imlet.2004.07.001. PMID 15388255.
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ (Jan 2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000071539 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021569 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7776974-5] Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (Feb 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Molecular Endocrinology. 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974.

[entrez-6] "Entrez Gene: TRIP13 thyroid hormone receptor interactor 13".

[pmid16189514-7] Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

[pmid16169070-8] Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.

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Interactions

References

Further reading